What are Anti Rejection Drugs?
These drugs suppress resistance power of recipient’s body to prevent rejection of liver graft from other person. They are essential for sustaining liver graft and are to be taken for life long.
Why are Anti Rejection Drugs (Immunosuppressant Drugs) needed?
One’s body doesn’t accept other’s organ. It is body’s defense system to try to attack and destroy other’s organ. Anti rejection drugs makes defense mechanism weak against donor’s organ and allow liver graft to sustain and work normally.
How do Anti Rejection Drugs (Immunosuppressant Drugs) work?
The immune system is our body’s natural defense mechanism. It is programmed to recognize and destroy anything unfamiliar. This includes the cells of a transplanted liver as well as the bacteria and organisms that cause infection. Following a liver transplant, specific drugs are needed to prevent the immune system from rejecting the new liver. These are called immunosuppressant drugs, and you will have to take them every day for the rest of your life.
A combination of the following Anti Rejection Drugs (Immunosuppressant Drugs) is prescribed:
All of these Anti Rejection Drugs (Immunosuppressant Drugs) will increase your risk of infection. During the first few months after transplantation the need for immunosuppression is at its highest. This is the time when you are at most risk from infection. The risk decreases when the doses are reduced after several months. Besides, it is advised to avoid close contact with people with infections e.g. chicken pox, flu. You will be monitored very closely for signs of infection and treated if necessary. Regular blood samples will determine the level of these drugs and the daily done will be changed if required by the transplant surgeon. If the levels are too low the risk of rejection is greater and the doses are increased. If the levels are too high you may experience more side effects and the doses are reduced. You must never alter the dose of your immunosuppression by yourself. Failure to take these medicines as prescribed can result in rejection of your new liver.
What are the possible side effects of these Anti Rejection Drugs (Immunosuppressant Drugs)?
Like most medicines, Immunosuppressant drugs too have some unwanted side effects. Although Immunosuppressant drugs are known to cause certain side effects, it does not necessarily mean that you will experience all or any of them. These drugs are safe and have been used for a long time. Other medicines are available to help treat troublesome side effects. The following side effects may be experienced:
- High blood pressure
- Increased/ unusual hair growth
- Sore or swollen gums
- Shaky hands
- Increased appetite
- Mood changes
- Weight Gain
- Irritation of stomach lining
- Fragile Skin
- Thinning of the bones (osteoporosis)
- Unsual bleeding or bruising
- Hair loss
- Nausea and vomiting
- Increase risk of skin
- Damage by sun exposure
- Nausea and vomiting
- High Blood Pressure
- Fluid retention
- Mouth ulcers
-Low platelet and white cells count
- Increased cholesterol
- Increased blood sugar / diabetes
- Visual problems
- Shaky hands/ aching joint
What other medicines do I have to take ?
For the first three months after transplantation you need to take the following medicines.
- Antibiotics – to reduce the risk of bacterial infections
- Antifungal liquid – to reduce the risk of fungal infection in you mouth
- Antacid – to reduce the risk of stomach ulcers and heartburn
- Any other medicines that you have to take will be prescribed for you depending on your symptoms.
Where should I get treated illness not related to transplant?
You should go to qualified doctor for consultation. Do not change or stop medicine on your own. If you have any concerns about your medicines do not hesitate to ask a member of the team.
Consult regarding all your problems related Liver Disease, Liver Transplant, Living Donor, Cadaveric Donor, Pre-Transplant Preparation, Peri or Post Transplant Care, Organ Transplant Act in India and abroad, Liver Transplant in India, China, Singapore etc.or any queries related to this field.
Send your latest following reports for an expert opinion by Dr. Jyotsna Verma:
CBC, LFT, PT(INR), S.Creatinine, Alpha Feto Protein (AFP)
USG/CT Scan Abdomen, Current Treatment / Medicine Chart
India Liver Transplant provides information on liver transplant in India and abroad, cost of liver transplant, success rate of liver transplant, liver transplant in China, liver transplant in Delhi, about pros and cons of liver surgery, treatment for common liver diseases, cirrhosis, jaundice, hepatitis, liver donor, risks to liver donor's life, cadaveric liver transplant, liver cancer treatment, liver transplant medicines, post liver transplant life, care, precautions and sucess rate, acute liver failure by India's most experienced liver transplant coordinator Jyotsna Verma who worked with pioneers of Liver transplant surgery in India, Dr. A. S. Soin, Dr. Samiran Nundy, Dr. Subash Gupta, Dr. Vivek Vij, Dr. Rahul Kakodkar, Dr. Vinay Kumaran, Dr. Mohammed Rela, Dr. Anand Ramamurthy, and worked with best liver transplant team at Liver Transplant Unit Sir Ganga Ram Hospital(SGRH), Institute of Liver Transplantation and Regenerative Medicines, Medanta - The Medicity, Gurgaon and Fortis Hospitals, NOIDA and has been to ILBS (Institute of Liver and Biliary Sciences).
Last Update: 2015/09/24 Next Update Due:2015/10/25 Test Update(Japan, Korea, Switzerland and France) :2015/09/22-29
All rights reserved. Universal Copyrights (Sans USA) - 38911022 and 17914070 © (2012-2016)
[Liver Transplant in India]: Jyotsna Verma ( Liver Transplant Consultant(India) )
This page provides information on:
side effects of immunosuppressant drugs, side effects of anti rejection drugs, side effects of liver transplant medicines, side effects of Sirolimus, side effects of Mycophenolate Mofetil , side effects of Tacrolimus, side effects of Azathioprine, side effects of Prednisolone, side effects of Cyclosporine, immunosuppressant drugs, anti rejection drugs, liver transplant medicines